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Charge reduction of pegylated proteins

Determination of PEGylated proteins' intact mass by mass spectrometry is challenging due to the molecules' large size, excessive charges, and more.

Released By Bora Biologics

Abstract
Determination of PEGylated proteins’ intact mass by mass spectrometry is challenging due to the molecules’ large size, excessive charges, and instrument limitations. Previous efforts have been reported. However, signal variability, ion coalescence, and a generally low degree of robustness have been observed. Click here to read more >>>

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